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Endometrial cancer is the fourth most common cancer affecting women in the United States, with an incidence of 27 per 100,000 and a death rate of 4.9 in 100,000. The average age of diagnosis is 60 years old, although diagnosis in younger women is becoming more common. Recurrence of early-stage endometrial cancer without significant adverse risk factors is uncommon, but recurrence of early-stage disease with high-intermediate or high-risk features or with advanced disease can be significant.

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