Lymphatic fluid is composed of water, protein, and other debris emited from capillary
beds into the intersitium
Keywords
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References
- Fibrosis and secondary lymphedema: chicken or egg?.Transl Res. 2019; 209: 68-76
- Ras pathways on Prox1 and Lymphangiogenesis: insights for therapeutics.Front Cardiovasc Med. 2020; 7: 597374
- Regulatory T Cells mediate local immunosuppression in lymphedema.J Invest Dermatol. 2018; 138: 325-335
- Földi’s Textbook of Lymphology.3rd edition. Mosby, 2012
- A primer on lymphedema.1st edition. Prentice Hall, Hoboken, New Jersey2004
- Mechanosensation and Mechanotransduction by Lymphatic endothelial cells act as important regulators of lymphatic development and function.Int J Mol Sci. 2021; 22: 3955
- Lymphedema, A concise compendium of theory and practice.Springer-Verlag, Berlin/Heidelberg, Germany2011
- Lymphovenous anastomosis aids wound healing in lymphedema: relationship between lymphedema and delayed wound healing from a view of immune mechanisms.Adv Wound Care (New Rochelle). 2019; 8: 263-269
- The unresolved pathophysiology of lymphedema.Front Physiol. 2020; 11: 137
- Modulation of immunity by lymphatic dysfunction in lymphedema.Front Immunol. 2019; 10: 76
- Lymphedema and subclinical lymphostasis (microlymphedema) facilitate cutaneous infection, inflammatory dermatoses, and neoplasia: a locus minoris resistentiae.Clin Dermatol. 2014; 32: 599-615
- Impact of ipsilateral blood draws, injections, blood pressure measurements, and air travel on the risk of lymphedema for patients treated for breast cancer.J Clin Oncol. 2016; 34: 691-698
- Axillary treatment for operable primary breast cancer.Cochrane Database Syst Rev. 2017; 1: Cd004561
- Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial.JAMA. 2011; 305: 569-575
- Radiation field design in the ACOSOG Z0011 (Alliance) Trial.J Clin Oncol. 2014; 32: 3600-3606
- Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial.Lancet Oncol. 2013; 14: 297-305
- Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial.Lancet Oncol. 2014; 15: 1303-1310
- Radiation therapy targets and the risk of breast cancer-related lymphedema: a systematic review and network meta-analysis.Breast Cancer Res Treat. 2017; 162: 201-215
- Regional nodal irradiation in early-stage breast cancer.N Engl J Med. 2015; 373: 307-316
- The impact of radiation therapy on the risk of lymphedema after treatment for breast cancer: a prospective cohort study.Int J Radiat Oncol Biol Phys. 2014; 88: 565-571
- Does axillary boost increase lymphedema compared with supraclavicular radiation alone after breast conservation?.Int J Radiat Oncol Biol Phys. 2008; 72: 1449-1455
- Quantifying the impact of axillary surgery and nodal irradiation on breast cancer–related lymphedema and local tumor control: long-term results from a prospective screening trial.J Clin Oncol. 2020; 38: 3430-3438
- Internal mammary and medial supraclavicular irradiation in breast cancer.New Engl J Med. 2015; 373: 317-327
- Radiation therapy field design and lymphedema risk after regional nodal irradiation for breast cancer.Int J Radiat Oncol Biol Phys. 2018; 102: 71-78
- Determining the organ at risk for lymphedema after regional nodal irradiation in breast cancer.Int J Radiat Oncol Biol Phys. 2019; 105: 649-658
- Results of a pooled analysis of IOERT containing multimodality treatment for locally recurrent rectal cancer: Results of 565 patients of two major treatment centres.Eur J Surg Oncol. 2017; 43: 107-117
- The need for preoperative baseline arm measurement to accurately quantify breast cancer-related lymphedema.Breast Cancer Res Treat. 2016; 157: 229-240
- Standardized method for quantification of developing lymphedema in patients treated for breast cancer.Int J Radiat Oncol Biol Phys. 2011; 79: 1436-1443
- Defining a threshold for intervention in breast cancer-related lymphedema: what level of arm volume increase predicts progression?.Breast Cancer Res Treat. 2013; 140: 485-494
- Preoperative assessment enables the early diagnosis and successful treatment of lymphedema.Cancer. 2008; 112: 2809-2819
- The diagnosis and treatment of peripheral lymphedema: 2020 consensus document of the international society of lymphology.Lymphology. 2020; 53: 3-19
- Interventions for breast cancer-related lymphedema: clinical practice guideline from the academy of oncologic physical therapy of APTA.Phys Ther. 2020; 100: 1163-1179
- Timing of lymphedema after treatment for breast cancer: when are patients most at risk?.Int J Radiat Oncol Biol Phys. 2019; 103: 62-70
- Földi’s textbook of lymphology. For physicians and lymphedema therapists.3rd edition. Urban & Fischer, Amsterdam, Netherlands2012
- Chapter 31: complete decongestive physiotherapy.Lymphedema Springer International Publishing AG, London, UK2018
- Exercise guidelines for cancer survivors: consensus statement from international multidisciplinary roundtable.Med Sci Sports Exerc. 2019; 51: 2375-2390
- Weight lifting for women at risk for breast cancer-related lymphedema: a randomized trial.Jama. 2010; 304: 2699-2705
- Randomized trial of decongestive lymphatic therapy for the treatment of lymphedema in women with breast cancer.J Clin Oncol. 2013; 31: 3758-3763
- Complex decongestive lymphatic therapy with or without vodder ii manual lymph drainage in more severe chronic postmastectomy upper limb lymphedema: a randomized noninferiority prospective study.J Pain Symptom Manage. 2015; 50: 750-757
- Effect of low-level laser therapy on pain and swelling in women with breast cancer-related lymphedema: a systematic review and meta-analysis.J Cancer Surviv. 2015; 9: 287-304
- Integrated treatment of breast cancer-related lymphedema: a descriptive review of the state of the art.Anticancer Res. 2021; 41: 3233-3246
- Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis.Lancet Oncol. 2013; 14: 500-515
- The use of a microscope with near-infrared imaging function in indocyanine green lymphography and lymphaticovenous anastomosis.J Plast Reconstr Aesthet Surg. 2014; 67: 231-236
- Indocyanine green-enhanced lymphography for upper extremity lymphedema: a novel severity staging system using dermal backflow patterns.Plast Reconstr Surg. 2011; 128: 941-947
- The feasibility and oncological safety of axillary reverse mapping in patients with breast cancer: a systematic review and meta-analysis of prospective studies.PLoS One. 2016; 11: e0150285
- A comprehensive overview on the surgical management of secondary lymphedema of the upper and lower extremities related to prior oncologic therapies.BMC Cancer. 2017; 17: 468
- A prospective analysis of 100 consecutive lymphovenous bypass cases for treatment of extremity lymphedema.Plast Reconstr Surg. 2013; 132: 1305-1314
- From theory to evidence: long-term evaluation of the mechanism of action and flap integration of distal vascularized lymph node transfers.J Reconstr Microsurg. 2015; 31: 26-30
- Long-term results of microvascular lymph node transfer: correlation of preoperative factors and operation outcome.Plast Reconstr Surg Glob Open. 2021; 9: e3354
- Reverse lymphatic mapping: a new technique for maximizing safety in vascularized lymph node transfer.Plast Reconstr Surg. 2015; 135: 277-285
- Intra-abdominal Lymph nodes: a privileged donor site for vascularized lymph node transfer.Plast Reconstr Surg Glob Open. 2020; 8: e2673
- Vascularized jejunal mesenteric lymph node transfer: a novel surgical treatment for extremity lymphedema.J Am Coll Surg. 2017; 225: 650-657
- Liposuction in lymphedema treatment.J Reconstr Microsurg. 2016; 32: 56-65
- Evaluation of simplified lymphatic microsurgical preventing healing approach (S-LYMPHA) for the prevention of breast cancer-related clinical lymphedema after axillary lymph node dissection.Ann Surg. 2019; 270: 1156-1160
- Near-infrared fluorescence imaging for the prevention and management of breast cancer-related lymphedema: A systematic review.Eur J Surg Oncol. 2019; 45: 1778-1786
- Surgical management of lymphedema: a review of current literature.Gland Surg. 2020; 9: 503-511
- The effect of prophylactic lymphovenous anastomosis and shunts for preventing cancer-related lymphedema: a systematic review and meta-analysis.Microsurgery. 2018; 38: 576-585
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Published online: April 07, 2022
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